CleanPlex®周期性发烧综合征面板是一种预先设计和定制的基于多重PCR /扩增子的靶向测序(NGS)分析方法,旨在检查与周期性发烧综合征相关的16个基因的种系变异或突变。该小组针对这些基因的所有外显子区域和侧翼内含子序列。仅需10 ng DNA即可兼容测序就绪的文库,只需3个小时即可使用简化的工作流程进行准备。预先设计的面板经过计算机优化,可提供具有高目标性能和高覆盖均匀性的数据,以确保有效利用测序读数。
该产品是定做的。收到您的订单后,我们将合成面板,该套件将包含CleanPlex Multiplex PCR引物和CleanPlex Targeted Library Kit。可以分别订购CleanPlex索引PCR引物和CleanMag®磁珠,以完成从输入DNA到可测序的NGS文库的工作流程。
贮存温度
储存在-20°C。
仅供研究使用。不用于诊断过程。
Gene List: ADA2, CARD14, ELANE, IL36RN, LPIN2, MEFV, MVK, NLRC4, NLRP12, NLRP3, NOD2, PSMB8, PSTPIP1, TNFAIP3, TNFRSF1A, TRNT1 References: Kaya et al. Coexistence of familial Mediterranean fever and juvenile idiopathic arthritis with osteoporosis successfully treated with etanercept. Intern Med. 2010;49:619–22. Zhang et al. Genomic variations of the mevalonate pathway in porokeratosis. Elife. 2015 Jul 23;4:e06322. Soylemezoglu et al. Unresponsiveness to colchicine therapy in patients with familial Mediterranean fever homozygous for the M694V mutation. J Rheumatol. 2010;37:182–9.
Gene List: ADA2, CARD14, ELANE, IL36RN, LPIN2, MEFV, MVK, NLRC4, NLRP12, NLRP3, NOD2, PSMB8, PSTPIP1, TNFAIP3, TNFRSF1A, TRNT1
References: Kaya et al. Coexistence of familial Mediterranean fever and juvenile idiopathic arthritis with osteoporosis successfully treated with etanercept. Intern Med. 2010;49:619–22.
Zhang et al. Genomic variations of the mevalonate pathway in porokeratosis. Elife. 2015 Jul 23;4:e06322.
Soylemezoglu et al. Unresponsiveness to colchicine therapy in patients with familial Mediterranean fever homozygous for the M694V mutation. J Rheumatol. 2010;37:182–9.