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2016
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2015
Hamamoto, A., Kobayashi, Y. & Saito, Y. Identification of amino acids that are selectively involved in Gi/o activation by rat melanin-concentrating hormone receptor 1. Cell. Signal. 27, 818–827 (2015).
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2014
Beckert, U. et al. Biochemical and Biophysical Research Communications cNMP-AMs mimic and dissect bacterial nucleotidyl cyclase toxin effects. Biochem. Biophys. Res. Commun. 451, 497–502 (2014).
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Febles, N. K., Ferrie, A. M. & Fang, Y. Label-Free Single Cell Kinetics of the Invasion of Spheroidal Colon Cancer Cells through 3D Matrigel. Anal. Chem. 86, 8842–8849 (2014).
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Orgovan, N. et al. Dependence of cancer cell adhesion kinetics on integrin ligand surface density measured by a high-throughput label-free resonant waveguide grating biosensor. Sci. Rep. 4, 4034 (2014).
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2013
Sundström, L., Greasley, P. J., Engberg, S., Wallander, M. & Ryberg, E. Succinate receptor GPR91 , a G ai coupled receptor that increases intracellular calcium concentrations through PLC b. FEBS Lett. 587, 2399–2404 (2013).
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Morse, M., Sun, H., Tran, E., Levenson, R. & Fang, Y. Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family. BMC Pharmacol. Toxicol. 14, 1–18 (2013).
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Christiansen, E. et al. Discovery of a Potent and Selective Free Fatty Acid Receptor 1 Agonist with Low Lipophilicity and High Oral Bioavailability. J. Med. Chem. 56, 982–992 (2013).
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Deng, H., Sun, H. & Fang, Y. Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J. Pharmacol. Toxicol. Methods 68, 1–24 (2014).
Zaytseva, N. et al. Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion. Sens. Actuators B Chem. 1–17 (2013).
Zhao, H., French, J. B., Fang, Y. & Benkovic, S. J. The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans. Chem. Commun. (Camb). 49, 1–17 (2014).
Cho, Y. & Baldán, A. Quest for New Biomarkers in Atherosclerosis. Mo. Med. 110, 325–330 (2013).
Hennen, S. et al. Decoding Signaling and Function of the Orphan G Protein– Coupled Receptor GPR17 with a Small-Molecule Agonist. Sci. Signal. 6, 1–33 (2014).
Deng, H. & Fang, Y. The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists. Pharmaceuticals 6, 500–509 (2013).
Deng, H., Wang, C. & Fang, Y. Label-free cell phenotypic assessment of the molecular mechanism of action of epidermal growth factor receptor inhibitors. RSC Adv. 3, 10370–10378 (2013).
Schrage, R. et al. Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor. Br. J. Pharmacol. 169, 357–370 (2013).