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biomomentum厂家Arthro-BST™压关节软骨电位电-机械性质测量分析仪器系统

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  • 产品名称: biomomentum厂家Arthro-BST™压关节软骨电位电-机械性质测量分析仪器系统
  • 产品型号:Arthroscopic Probe
  • 产品展商:biomomentum
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简单介绍

在软骨评估中,现行的关节软骨定量测量方法不能及时发现早期退行性改变。Arthro-BST™是一种新的医疗设备(图1),可与关节镜连用来定量测量关节软骨。科技文献表明,流动电位既是软骨的函数,又是软骨成分、结构和厚度的函数。Arthro-BST™可测量轻压关节软骨时产生的流动电位,将其作为反映软骨电-机械性质的参数。

产品描述

 

系统简介:

在软骨评估中,现行的关节软骨定量测量方法不能及时发现早期退行性改变。Arthro-BST™是一种新的医疗设备(图1),可与关节镜连用来定量测量关节软骨。科技文献表明,流动电位既是软骨的函数,又是软骨成分、结构和厚度的函数。Arthro-BST™可测量轻压关节软骨时产生的流动电位,将其作为反映软骨电-机械性质的参数。

 

Arthro-BST™适用于测量软骨中压力导致的流动电位(图2 A)。在测量时,通常用一个一次性无菌探针来轻压关节软骨表面,然后记录产生的电信号。探针是一个覆盖有37个微电*的球形表面(图2 B)。仪器会记录下来当探针与软骨接触时总流动电位达到100 mV时使用的微电*数,作为软骨电机械活动的定量参数(QP)。高QP表示软骨的电机械性质较弱,低QP表示软骨的电机械性质较强(图2 C)。

 

应用范围:

Arthro-BST™在软骨修复研究中有着重要的应用。

l  有助于理解软骨**(如软骨退行)的发病原因

l  开发新的**产品和软骨修复技术

l  构建稳定的关节炎动物模型

 

应用文献:

Scientific Publications & Material Related to Arthro-BST™

2016

S. Sim, C. Becher, M. Garon, E. Quenneville, C. Hurschler and M.D. Buschmann. Comparison Between In Vitro and Simulated Arthroscopy Electromechanical Measurements of Human Articular Surfaces Using the Arthro-BST. International Cartilage Repair Society, Sorrento, Italy, Sept 2016. Poster #132

Sim S, Chevrier A, Garon M, Quenneville E, Lavigne P, Yaroshinsky A, Hoemann CD, Buschmann MD. Electromechanical probe and automated indentation maps are sensitive techniques in assessing early degenerated human articular cartilage. J Orthop Res. 2016 Jun 9. doi: 10.1002/jor.23330.Abstract

Jan C. Schagemann, Nicola Rudert, Michelle E. Taylor, Sotcheadt Sim, Eric Quenneville, Martin Garon, Mathias Klinger, Michael D. Buschmann, and Hagen Mittelstaedt (2016) Bilayer Implants: Electromechanical Assessment of Regenerated Articular Cartilage in a Sheep Model. Cartilage, 1947603515623992, first published on January 22, 2016. Abstract

2015

Mickevicius, T., Pockevicius, A., Kucinskas, A., Gudas, R., Maciulaitis, J., Noreikaite, A., and Usas, A. (2015). Impact of storage conditions on electromechanical, histological and histochemical properties of osteochondral allografts. BMC musculoskeletal disorders, 16(1), 314. Abstract, Article

Hadjab I., Sim S., E. Quenneville, M. Garon and M.D. Buschmann. (2015) Assessment of Human Articular Cartilage Issued from Asymptomatic and TKR Donors. Biomedical Engineering Society (BMES) Annual Meeting, Tampa, FL, USA. Presentation OP-Thurs-3-8. Thursday, October 8, 2015, 4:30 PM - 6:00 PM, Room 14.

Christoph Becher, Marcel Ricklefs, Elmar Willbold, Christof Hurschler, and Reza Abedian (2015) Electromechanical Assessment of Human Knee Articular Cartilage with Compression-Induced Streaming Potentials, Cartilage, 1947603515599191, first published on August 13, 2015. Abstract

S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores and Mechanical Properties in Human Tibial Plateau. Podium presentation 23.2.8 Osteoarthritis - Basic Science 2 and Biomechanics, Monday, May 11, 10:00 - 11:30, Chicago 9. Abstract / Presentation

S. Sim, I. Hadjab, M. Garon, E. Quenneville, M.B. Hurtig, M.D. Buschmann, and C.D. Hoemann. Evaluation of Entire Ovine Cartilage Repair Articular Surfaces: Mechanical and Electromechanical Assessment. Poster Presentation (P87). Abstract / Poster / ePoster

J.C. Schagemann, N. Rudert, S. Sim, E. Quenneville, M. Garon, M.E. Casper, M. Klinger, M.D. Buschmann, and H. Mittelstaedt. Correlation of Traditional and Novel Outcome Measures for the Assessment of Regenerated Osteochondral Tissue in a Sheep Model. Poster Presentation (P83). Abstract / Poster

S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores and Mechanical Properties in Human Tibial Plateau. OARSI 2015 World Congress on Osteoarthritis, April 30-3, 2015, Seattle, USA. Poster 368

S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores and Mechanical Properties in Human Tibial Plateau. 61st Annual Meeting of the ORS, March 28-30, 2015, Las Vegas, USA.Poster 1228

2014

S. Sim, A. Chevrier, M. Garon, E. Quenneville, A. Yaroshinsky, C.D. Hoemann and M.D. Buschmann. Non-destructive Electromechanical Assessment (Arthro-BST) of Human Articular Cartilage Correlates with Histological Scores and Biomechanical Properties. Osteoarthritis and Cartilage, 2014 Aug 25. pii: S1063-4584(14)01221-7. Abstract

A. Changoor, W. Brett, M.A. Hoba, M. Garon, E. Quenneville, K. Gordon, P. Savard, M.D. Buschmann, M.B. Hurtig and D.R. Trout. Electroarthrography, a non-invasive streaming potential-based method, measures cartilage quality in live horses. Osteoarthritis and Cartilage, Vol. 22, Supplement 1, 138, World Congress on Osteoarthritis, April 2014, Paris, France. Poster

S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores, Biochemical Composition and Mechanical Properties in Human Knee Joints. Transactions of the 60th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 0439. Poster

A. Changoor, M.A. Hoba, M. Garon, E. Quenneville, K. Gordon, P. Savard, M.D. Buschmann, M.B. Hurtig. Non-invasive Electroarthrography Correlates to Direct Measurements of Cartilage Streaming Potentials in Weight Bearing Regions of Equine Metacarpophalangeal (Fetlock) Joints. Transactions of the 60th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 1123. Poster

2013

S. Sim, A. Chevrier, E. Quenneville, M. Garon, and M.D. Buschmann. Correlation of Non-destructive Electromechanical Probe (Arthro-BST) Assessment with Histological Scores and Mechanical Properties in Human Knee Joints. Transactions International Cartilage Repair Society, P26, September 2013, Izmir, Turkey. Poster

Sim S., Picard G., Quenneville E., Garon M. and Buschmann M.D. (2013) The Spatial Pattern of Articular Cartilage Electromechanical Properties in the Stifle Joint is Similar in Three Different Species. Ecole Polytechnique of Montreal, Chemical Engineering Research Day, March 14th 2013. Presentation

Abedian R., Willbold E., Becher C. and Hurschler C. (2013) In vitro electro-mechanical characterization of human knee articular cartilage of different degeneration levels: A comparison with ICRS and Mankin scores. Journal of Biomechanics, accepted 5 February 2013, published online 11 March 2013.Abstract

Sim S., Picard G., Quenneville E., Garon M. and Buschmann M.D. (2013) The Spatial Pattern of Articular Cartilage Electromechanical Properties in the Stifle Joint is Similar in Three Different Species. Transactions of the 59th Annual Meeting of the Orthopaedic Research Society, San Antonio, TX, USA, 1975. Poster

Sim S., Picard G., Quenneville E., Garon M. and Buschmann M.D. (2013) Age-dependence of the Pattern of Cartilage Electromechanical Properties in the Ovine Stifle Joint Transactions of the 59th Annual Meeting of the Orthopaedic Research Society, San Antonio, TX, USA, 1976. Poster

Changoor A., Hoba M.A., Quenneville E., Garon M., Gordon K., Buschmann M.D., Savard P., Hurtig M.B. (2013) Electroarthrography Provides a Non-invasive Streaming Potential-Based Method for Detecting Cartilage Degeneration in an Equine Model Transactions of the 59th Annual Meeting of the Orthopaedic Research Society, San Antonio, TX, USA, 1974. Poster

2012

Sim S., Picard G., Quenneville E., Garon M. and Buschmann M.D. (2012) The Spatial Pattern of Articular Cartilage Electromechanical Properties in the Stifle Joint is Similar in Three Different Species. Groupe de recherche en sciences et technologies biomédicales (GRSTB) Symposium - Biomechanics and biomaterials, October 10, 2012, École Polytechnique de Montreal, Montreal, Quebec, Canada. Poster

2011

Presentation by Prof. Dr. Daniël Saris, MD, PhD of the Arthro-BST at the ICRS 4th Surgical Skills Course, in Rostock (Germany), August 25-27, 2011.Video 

Report following the ICRS Laboratory Skills Course in Translational Science in Montreal (Quebec, Canada), from May 31 to June 3, 2011. Report

Changoor, A., Coutu, J. P., Garon, M., Quenneville, E., Hurtig, M. B., Buschmann, M. D. (2011) Streaming Potential-Based Arthroscopic Device is Sensitive to Cartilage Changes Immediately Post-Impact in an Equine Cartilage Injury Model. J. Biomech. Eng. 2011 Jun. 133(6):061005. Abstract

Changoor, Adele (2011) Electromechanical And Polarization Microscopy Evaluation Of Cartilage Repair And Degeneration, Ecole Polytechnique of Montreal, Ph.D. thesis. Thesis

2010

Changoor A, Fereydoonzad L, Yaroshinsky A, Buschmann MD. (2010) Effects of refrigeration and freezing on the electromechanical and biomechanical properties of articular cartilage. J Biomech Eng. 2010 Jun;132(6):064502. Abstract

2009

Changoor A., Quenneville E., Garon M., Hurtig M.B., Buschmann, M.D., (2009) Streaming Potential-Based Arthroscopic Device Can Detect Changes Immediately Following Localized Impact in an Equine Impact Model of Osteoarthritis. Osteoarthritis and Cartilage, Vol. 17, Supplement 1, S53, World Congress on Osteoarthritis, September 2009, Montreal, Quebec, Canada. Poster

2008

Hurtig M.B., Quenneville E., Garon M., Buschmann M.D. Legare A. (2008) Evaluation of a Medical Device for Assessment of Cartilage Degeneration After Impact Injury. Transactions of the 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA, 33:723. Poster

Garon M., Buschmann M.D., (2008) Non-Homogeneous Electromechanical Properties of articular Cartilage Predict an Electrical Potential of Positive Polarity outside Cartilage. Transactions of the 54th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA, 33:629. Poster

2007

Changoor A., Quenneville E., Garon M., Cloutier L., Hurtig M.B., Buschmann, M.D., (2007) Streaming Potential-Based Arthroscopic Device Discerns Topographical Differences In Cartilage Covered And Uncovered By Meniscus In Ovine Stifle Joints. Transactions of the 53th Annual Meeting of the Orthopaedic Research Society, San Diego, CA, USA, 32:631. Poster

Garon, Martin (2007) Conception et validation d'une sonde arthroscopique pour l'évaluation des propriétés électromécaniques fonctionnelles du cartilage articulaire (Conception and Validation of an Arthroscopique Probe for Evaluation of Functional Electromechanical Properties of Articular Cartilage), Ecole Polytechnique of Montreal, Ph.D. thesis. Thesis (in French with Abstract in English)

Garon M., Legare A., Quenneville E., Sims T.J., Hollander A.P., Shive M.S., Restrepo A., Buschmann M.D., (2007) Arthroscopic Device Measuring Streaming Potentials Reliably indicates Functional Properties of Cartilage. Osteoarthritis and Cartilage, Vol. 15, Supplement C, 254, World Congress on Osteoarthritis, December 2007, Ft. Lauderdale, Florida, USA. Poster

Garon M., Legare A., Quenneville E., Sims T.J., Hollander A.P., Hurtig M.B., Shive M.S., Buschmann M.D., (2007) Cartilage Streaming Potentials Measured with an Arthroscopic Medical Device Correlate with Site-specific Biochemical and Biomechanical Properties of Equine Articular Cartilage. Transactions International Cartilage Repair Society, 22.6, September 2007, Warsaw, Poland. Slides

Garon M., Legare A., Quenneville E., Sims T.J., Hollander A.P., Shive M.S., Restrepo A., Buschmann M.D., (2007) Streaming Potentials Measured with an Arthroscopic Medical Device are Reliable Indicators of Biochemical and Biomechanical Properties of Human Articular Cartilage. Transactions International Cartilage Repair Society, 5.3, September 2007, Warsaw, Poland. Slides

Garon M., Cloutier L., Legare A., Quenneville E., Shive M.S., Buschmann M.D., (2007) Reliability and Correlation to Human Articular Cartilage Mechanical Properties of a Streaming Potential based Arthroscopic Instrument. Transactions of the 53th Annual Meeting of the Orthopaedic Research Society, San Diego, CA, USA, 32:629. Poster

Larouche, Antoine (2007) Détermination de l'épaisseur du cartilage articulaire par mesures de la conductivité électrique (Determination of Articular Cartilage Thickness by Electrical Conductivity Measurements), Ecole Polytechnique of Montreal, Master in Applied Science (M.A.Sc.) Thesis.
Master Thesis (in French with Abstract in English)

Quenneville E, Garon M, Légaré A, Shive M, and Buschmann MD (2007a). Mapping Articular Cartilage Function using a Streaming Potential-based Arthroscopic Device. Transactions of the Segal North American Osteoarthritis Workshop (Chicago, USA). Poster

Quenneville E, Buschmann MD (2007b). A novel approach to predict diagnostic electric potential in cartilage. Transactions of the Orthopedic Research Society. 32 630. Poster | Abstract

2006

Changoor A., Quenneville E., Garon M., Cloutier L., Légaré A., Hurtig M.B., Buschmann M.D. (2006). Streaming potential-based arthroscopic device discerns topographical differences in cartilage covered and uncovered by meniscus in ovine stifle joints. Transactions of the Canadian Arthritis Network (Winnipeg, Canada). Poster

Li LP, Herzog W., (2006). Arthroscopic evaluation of cartilage degeneration using indentation testing--influence of indenter geometry. Clin. Biomech. May;21(4):420-6. Epub 2006 Feb 2. Abstract

Quenneville, Eric (2006) Les distributions de potentiel électrique dans le cartilage articulaire (Electrical Potential Distributions in Articular Cartilage), Ecole Polytechnique of Montreal, Ph.D. thesis. Thesis (in French with Abstract in English)

2005

Li LP, Herzog W., (2005). Electromechanical response of articular cartilage in indentation--considerations on the determination of cartilage properties during arthroscopy. Comput. Methods Biomech. and Biomed. Engin. Apr;8(2):83-91. Abstract

Quenneville E, Garon M, Légaré A, Garon M, and Buschmann MD. (2005a) Arthro-BST: A Diagnostic Instrument for the Functional Evaluation of Articular Cartilage. AITS Innovation Research Contest, Montréal, Mars 2005 Slides

Quenneville E., and Buschmann M.D. (2005b), A transport model of convection of electrolyte through a charged membrane predicts generation of net charge at membrane interfaces. Journal of Membrane Science, 265 (1-2), 60-73, 2005. Abstract

2004

Buschmann, M. D., Légaré, A., Garon, M. and Savard, P. (2004). Characterization of the Contact Distribution between Two Arbitrary Surfaces using Electrode Arrays. Patent 1199983 (Germany).

Quenneville E., Garon M., Legare A., Buschmann M.D., (2004a) Positive Electric Potentials Detected at the Cartilage/Bath Interface During Compression and their Importance in Clinical Cartilage Diagnostics. Transactions of the 50th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA, 29:528. Poster

Quenneville E, Garon M, and Buschmann MD. (2004b) Convection of electrolyte through a charged membrane produces net charge at membrane interfaces. Polyelectrolytes 2004, #S2-23, Amherst, USA (2004) Poster

Quenneville, E., Binette, J. S., Garon, M., Legare, A., Meunier, M. and Buschmann, M. D. (2004c). Fabrication and characterization of nonplanar microelectrode array circuits for use in arthroscopic diagnosis of cartilage diseases. IEEE Trans Biomed Eng. 51(12): 2164-73. Abstract

2003

Garon M., Legare A., Quenneville E., Hurtig M., Buschmann M.D., (2003) Streaming Potential Based Arthroscopic Instrument Distinguishes Site-Specific Properties of Equine Articular Cartilage. Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 28:255.Slides | Abstract

Quenneville E., Garon M., Legare A., Hurtig M., Buschmann M.D., (2003a) Load and Streaming Potential Responses of Articular Cartilage as a Function of Compression Speed during Indentation. Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 28:659. Poster

Quenneville E, Garon M, Légaré A, Garon M, Buschmann MD. (2003b) New Arthroscopic Device for Functional Mapping of Articular Cartilage. Trans. Joint IXth Canadian Connective Tissue Conference, #SS-1, Montreal, Canada, July 2003.

2002

Buschmann MD, Légaré A, Quenneville E, Garon M, and Hurtig MB. (2002) Mapping of the Functional Properties of Articular Cartilage via Streaming Potentials Measured with a New Arthroscopic Device. Trans. Osteoarthritis Consensus Conference, Toronto, April 2002

Garon M., Legare A., Guardo R., Savard P., Buschmann, M.D. (2002) Streaming Potentials Maps are Spatially Resolved Indicators of Amplitude, Frequency and Ionic Strength Dependant Responses of Articular Cartilage to Load. Journal of Biomechanics. 35, pp.207-216. Abstract

Legare A., Garon M., Guardo R., Savard P., Buschmann, M.D. (2002) Detection and Analysis of Cartilage Degeneration by Spatially Resolved Streaming Potentials. Journal of Orthopaedic Research. 20(4), pp. 208-215. Abstract

Quenneville E, Garon M, Légaré A, Garon M, Hurtig M, Buschmann MD. (2002a) Diagnostic Mapping of Articular Cartilage with a New Arthroscopic Device. Trans. International Cartilage Repair Society, Toronto, June 2002. Poster

Quenneville E, Garon M, Légaré A, Garon M, Hurtig M, and Buschmann MD. (2002b) Diagnostic Mapping of Bovine and Equine Articular Cartilage with a New Arthroscopic Device. Trans. Canadian Arthritis Network, Calgary, September 2002 Slides

2001

Garon M, Guardo R, and Buschmann MD. (2001) Estimation and sensitivity to cartilage degradation of electromechanical coupling coefficients derived using spatially resolved streaming potentials. Trans. Orthopaedic Research Society. San Francisco, USA, February 2001. Poster

Légaré A, Garon M, Binette F and Buschmann MD. (2001) Evaluation of Cartilage Quality using Streaming Potential Maps. International Cartilage Repair Society, 2001. Poster

Quenneville E, Légaré A, Garon M, Buschmann MD. (2001) Evaluation of an Arthroscopic Probe for the diagnosis of Cartilage Degradation. Canadian Arthitis Network Conference, Calgary, September 2001. Poster

2000

Buschmann, MD. (2000) Spatial Resolution of Mechanical Phenomena in Loaded Cartilage. The Whitaker Foundation Conference, San Diego, August 2000.

Légaré A, Garon M, Binette F and Buschmann MD. (2000a) Evaluation of Cartilage Quality using Streaming Potential Maps. International Cartilage Repair Society, Sweden, April 2000. Poster

Légaré A. (2000b) Functionnal Evaluation of Joint Diseases and Repair through Arthroscopic Non-Destructive Streaming Potential Measurements. Emerging Medical Technologies, California, 2000

1999

Légaré A, Garon M, Binette F, Guardo R, Savard P, and Buschmann MD. (1999) Characterization of Connective Tissue Using Streaming Potential Maps. Transactions 5th Canadian Connective Tissue Conference. Montreal, Canada, June 1999. Slides

1998

Buschmann, M. D., Guardo, R., Garon, M., Savard, P. and Le Guyader, P. (1998). A medical device for the diagnosis of cartilage degeneration via spatial mapping of compression-induced electrical potentials. Patent 5779651 (United States).

Légaré, A. (1998a). Détection de la dégénérescence du cartilage articulaire par la distribution spatiale des potentiels d'écoulement (Detection of Articulare Cartilage Degeneration by Streaming Potentials Spatial Distribution), Biomedical Engineering Institute, Montreal, Ecole Polytechnique of Montreal. Master in Applied Science (M.A.Sc.) Thesis.

Legare A., Garon M., Guardo R., LeGuyader P., Savard P., Buschmann M.D. (1998b) Detection of Cartilage Degeneration by Spatially Resolved Streaming Potentials. Transactions of the 44th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, USA, 23:659. Slides

1997

Garon M., Guardo R., Savard P., Buschmann M.D. (1997) Spatially Resolved Detection of Streaming Potentials in Articular Cartilage. Transactions of the 43th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, USA, 22:80. Slides

 

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